GS
Genetic Screening
Preimplantation genetic testing may be used to screen eggs and/or embryos for a specific genetic disorder or for unbalanced chromosome products due to a parental chromosome abnormality. Indications for PGT include, but are not limited to, one or both intended parents being a carrier of a balanced chromosome translocation or inversion, having a known family history of genetic disorders, or being a carrier of or affected with a known genetic mutation and/or marker.
Genetic screening is for:
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Preimplantation genetic testing for aneuploidy (PGT-A)
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Monogenic (single gene) disorders (PGT-M)
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Chromosomal structural rearrangements (PGT-SR, most commonly seen as balanced translocations)
The process,
explained simply.
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In order to perform preimplantation genetic testing, the embryo must be biopsied. Embryo biopsy is an invasive but safe procedure and is typically performed on day 5 or 6 of embryo development by removing a few cells from the trophectoderm with a microsurgical needle.
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The cells are then genetically analyzed for abnormalities. During the screening process, the embryo will be cryopreserved until the results are available.
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These genetic results about each individual embryo will be presented to you, and together with your physicians, geneticist and IVF scientists, you will be offered the opportunity to specify which embryo or embryos you elect to have returned to you in the hopes of producing a healthy pregnancy. You will also be given the opportunity to store any healthy unutilized embryos for future transfer.
